Meanings of living at home on a ventilator Nine adults were interviewed in order to illuminate the meanings of being dependent on a ventilator and living at home. The data were analysed using a phenomenological‐hermeneutic method inspired by the philosophy of Ricoeur. Five main themes emerged through the analysis: experiencing home as a safe and comfortable space from which to reach out, experiencing the body as being frail, brave and resilient, striving to live in the present, surrendering oneself to and (...) trusting others, and experiencing technology as a burden and a relief to the lived body. Meanings of being home on a ventilator were interpreted as maintaining autonomy and persistence in interaction with the ventilator and other human beings and being able to rise above yourself and your personal boundaries in order to live a good life. These meanings indicate that aesthetic and ethical values impact on the lived body. They are bound up with experiencing a vital force and interdependency, bringing safety and courage into daily life. (shrink)

Background: Although convolutional neural networks (CNNs) achieve high diagnostic accuracy for detecting Alzheimer’s disease (AD) dementia based on magnetic resonance imaging (MRI) scans, they are not yet applied in clinical routine. One important reason for this is a lack of model comprehensibility. Recently developed visualization methods for deriving CNN relevance maps may help to fill this gap as they allow the visualization of key input image features that drive the decision of the model. We investigated whether models with higher accuracy (...) also rely more on discriminative brain regions predefined by prior knowledge. Methods: We trained a CNN for the detection of AD in N = 663 T1-weighted MRI scans of patients with dementia and amnestic mild cognitive impairment (MCI) and verified the accuracy of the models via cross-validation and in three independent samples including in total N = 1655 cases. We evaluated the association of relevance scores and hippocampus volume to validate the clinical utility of this approach. To improve model comprehensibility, we implemented an interactive visualization of 3D CNN relevance maps, thereby allowing intuitive model inspection. Results: Across the three independent datasets, group separation showed high accuracy for AD dementia versus controls (AUC ≥ 0.91) and moderate accuracy for amnestic MCI versus controls (AUC ≈ 0.74). Relevance maps indicated that hippocampal atrophy was considered the most informative factor for AD detection, with additional contributions from atrophy in other cortical and subcortical regions. Relevance scores within the hippocampus were highly correlated with hippocampal volumes (Pearson’s r ≈ −0.86, p < 0.001). Conclusion: The relevance maps highlighted atrophy in regions that we had hypothesized a priori. This strengthens the comprehensibility of the CNN models, which were trained in a purely data-driven manner based on the scans and diagnosis labels. The high hippocampus relevance scores as well as the high performance achieved in independent samples support the validity of the CNN models in the detection of AD-related MRI abnormalities. The presented data-driven and hypothesis-free CNN modeling approach might provide a useful tool to automatically derive discriminative features for complex diagnostic tasks where clear clinical criteria are still missing, for instance for the differential diagnosis between various types of dementia. (shrink)

In seinen Vorlesungen über die Ästhetik hat Hegel einen der wichtigsten und wirkmächtigsten Beiträge zur Ästhetik und Philosophie der Kunst entwickelt. Von der systematischen Klärung der Idee des Schönen über die geschichtliche Unterscheidung der symbolischen, klassischen und romantischen Kunstform bis hin zur Darstellung der einzelnen Künste (Architektur, Skulptur, Malerei, Musik, Poesie) werden alle relevanten Aspekte entfaltet und miteinander vernetzt. Eindrucksvoll ist nicht nur Hegels plastischer Zugriff auf die Fülle konkreten Materials. Bedeutsam ist vor allem sein kulturphilosophischer Ansatz, der die Kunst (...) auf dem Rang des "absoluten Geistes" als zentrales Medium menschlicher Selbstverständigung begreift. Die vieldiskutierte These vom "Ende der Kunst" in der Moderne hängt damit direkt zusammen. Hegel hat seine vier Berliner Ästhetik-Kollegien nicht selbst publiziert. Dieser Kommentarband orientiert sich an der Edition des Hegel-Schülers H.G. Hotho und zieht ergänzend die Nachschriften, insbes. des letzten Kollegs von 1828/29 hinzu. In dieser Form wird Hegels Ästhetik auf dem aktuellen Forschungsstand für ein breites philosophisches und kulturwissenschaftliches Interessenfeld erschlossen. Mit Beiträgen von B. Collenberg-Plotnikov, N. Hebing, G. Hindrichs, S. Houlgate, W. Jaeschke, R. Pippin, B. Sandkaulen, U. Seeberg, M. Seel, A. Speight u. J. Stolzenberg. (shrink)

'Myth has not been really vanquished and subjugated. It is always there, lurking in the dark and waiting for its hour and opportunity' Ernst Cassirer, The Myth of the StateAs a central part of his philosophy of symbolic forms as a form of religious expression, and as a political problematic the question of myth belongs at the heart of Ernst Cassirer's intellectual enterprise. Using a variety of methodological and conceptual approaches, these papers examine the persistence of myth as a symbolic (...) form from a variety of perspectives: philosophical, anthropological, psychological, political, and historico-cultural. In its way each paper attempts, in Cassirer's phrase, to 'see the adversary face to face'.The contributors to this volume are Paul Bishop, Alan Cardew, Milad Doueihi, Dina Gusejnova, Cyrus Hamlin, Stefanie Hölscher, Kai Kresse, John Michael Krois, Barbara Naumann, Detlev Pätzold, Martine Prange, Birgit Recki, Edward Skidelsky, Roger Stephenson and Jonathan Westwood. (shrink)

Diese Festschrift für Michael Fischer ist ein Patchwork und eine wunderbare Mischung aus Wissenschaft, Persönlichem, Freundschaft und Genuss. Sie setzt sich aus unterschiedlichen und vielseitigen Texten, Zeichnungen und Bildern zusammen, von Menschen, die ihn begleitet haben, manche viele Jahre, manche nur eine kurze, aber entscheidende Zeit. Studentinnen und Studenten, die von ihm gelernt haben, Kolleginnen und Kollegen, die mit ihm Ideen entwickelt, Projekte initiiert und geforscht haben, Freunden aus Kunst und Kultur, Theater, Oper und den Bühnen des Lebens, nämlich: Eric (...) Hobsbawm, Claudio Magris, André Glucksmann, Wolf Singer, Johannes Hahn, Volker Gerhardt, Thomas Fischer, Rudolf (+) und Gundl Hradil, Helga Rabl-Stadler, Gerard Mortier, Jürgen Flimm, Brita Steinwendtner, Veit Heinichen, Peter Ruzicka, André Tubeuf, Thomas Oberender, Stefan Zweifel, Hermann Lübbe, Eduardo Chitas, Wilhelm Donner, Hans Eichhorn, Reinhard Kacianka, Tina Perisutti, Ulrich H. J. Körtner, Markus Hengstschläger, Henriette und Conrad Ulrich-Hürlimann, Michael Hagner, Thomas Macho, Johann Weyringer, Birgit Recki, Walther Ch. Zimmerli, Andreas Cesana, Kurt Seelmann. (shrink)

Patient support tools have drawn on a variety of disciplines, including psychotherapy, social psychology, and social care. One discipline that has not so far been used to support patients is philosophy. This paper proposes that a particular philosophical approach, phenomenology, could prove useful for patients, giving them tools to reflect on and expand their understanding of their illness. I present a framework for a resource that could help patients to philosophically examine their illness, its impact on their life, and its (...) meaning. I explain the need for such a resource, provide philosophical grounding for it, and outline the epistemic and existential gains philosophy offers. Illness often begins as an intrusion on one’s life but with time becomes a way of being. I argue that this transition impacts on core human features such as the experience of space and time, human abilities, and adaptability. It therefore requires philosophical analysis and response. The paper uses ideas from Husserl and Merleau-Ponty to present such a response in the form of a phenomenological toolkit for patients. The toolkit includes viewing illness as a form of phenomenological reduction, thematizing illness, and examining illness as altering the ill person’s being in the world. I suggest that this toolkit could be offered to patients as a workshop, using phenomenological concepts, texts, and film clips to reflect on illness. I conclude by arguing that examining illness as a limit case of embodied existence deepens our understanding of phenomenology. (shrink)

InhaltVorwort der Herausgeber Wilhelm G. JACOBS: Einleitung Hartmut TRAUB: Über die Freundschaft – Vier Bemerkungen zum Briefwechsel zwischen Schelling und Fichte Paul ZICHE: Raumkonstruktion, Deduktion der Dimensionen und idealistische Prinzipientheorie Problemlagen im Fichte-Schelling-Briefwechsel vom November 1800Christian KLOTZ: »Synthesis der Geisterwelt«. Fichtes Systemskizze im Briefwechsel mit Schelling Birgit SANDKAULEN: Was heißt Idealismus? Natur- und Transzendentalphilosophie im Übergang zur Identitätsphilosophie Schellings Systemskizze vom 19.11.1800Violetta L. WAIBEL: Fichtes Kritik an Schelling »Alle Wissenschaften sind nur Theile der Wissenschaftslehre« Zu Fichtes Briefen an Schelling (...) vom 31. Mai / 7. August 1801 und 15. Januar 1802 Lore HÜHN: Die Verabschiedung des subjektivitätstheoretischen Paradigmas. Der Grunddissens zwischen Schelling und Fichte im Lichte ihres philosophischen BriefwechselsPetra LOHMANN: Die Funktionen der Kunst und des Künstlers in der Philosophie Johann Gottlieb FichtesThomas KISSER: Wie kann eine allgemeine Theorie der Wirklichkeit ihre eigene Wahrheit zeigen? Bemerkungen und Fragen zu Struktur und Funktion der Kunst in Schellings System des transzendentalen Idealismus Zur Diskussion:Erklärung von Prof Dr. Maciej Potepa Editionspraxis in dürftiger Zeit am Beispiel der F. H. JacobiWerkeausgabe Band 3 von Albert Mues Vierter Internationaler Kongress der Russischen Fichte-Gesellschaft: »Platon, Machiavelli und Fichte – Die Idee einer gerechten Gesellschaft« vom 26. – 31. Mai 2004 in Ufa . Ein Reisebericht von Hartmut Traub Rezensionen. (shrink)

The dominant approach to environmental policy endorsed by conservative and libertarian policy thinkers, so-called “free market environmentalism”, is grounded in the recognition and protection of property rights in environmental resources. Despite this normative commitment to property rights, most self-described FME advocates adopt a utilitarian, welfare-maximization approach to climate change policy, arguing that the costs of mitigation measures could outweigh the costs of climate change itself. Yet even if anthropogenic climate change is decidedly less than catastrophic, human-induced climate change is likely (...) to contribute to environmental changes that violate traditional conceptions of property rights. Viewed globally, the actions of some countries—primarily industrialized nations—are likely to increase environmental harms suffered by other countries—less developed nations that have not made any significant contribution to climate change. It may well be that aggregate human welfare would be maximized in a warmer, wealthier world, or that the gains from climate change will offset environmental losses. Yet such claims, even if demonstrated, would not address the normative concern that the consequences of anthropogenic global warming would infringe upon the rights of people in less-developed nations. As a consequence, this paper calls for a rethinking of FME approaches to climate change policy. (shrink)

The words 'true value' assume an existential relationship with the thing being measured. There is assumed to exist some aspect of the thing being measured that is independent of its relationship to the person who is interested in the result of the measurement. Yet measurement is a response to the need of an observer to know something about the real world. There is therefore an epistemological aspect to measurement. Some aspect of measurement has to do with the observer as a (...) knower of the result of the measurement. The paper considers electrical measurement. It proposes that these relationships correspond to two distinct kinds of measurement: one has the characteristic that there does exist such a thing as a true value, though it cannot be known: in the other kind, no such thing as true value even exists. The notion of true value is very useful, and for the kind of measurement where such a thing does not exist, the paper defines an alternative that has the advantage that it can actually be known under some circumstances in calibration. (shrink)

_Early Psychoanalytic Religious Writings_ presents, in one edited volume, many of the foundational writings in the psychoanalytic study of religion. These translated works by Abraham, Fromm, Pfister, and others, complement Freud’s seminal contributions and provide a unique window into the origins of psychoanalytic thinking.

Criticism and interpretation of Zawāhir al-ḥikam by Ḥasan ibn ʻAbd al-Razzāq Lāhījī, 1635 or 1636-1709 or 1710; Islamic philosophy - Early works to 1800; Shīʻah - Doctrines - Early works to 1800.

Studying Mesilat Yesharim with Hadar Goldin.

Articles; chiefly on Islamic ethics and conveying non Muslims for Islam.

For two hundred years, Americans have believed that they have an obligation to improve the lot of humanity, a belief that has consistently shaped U.S. foreign policy. Yet within this consensus, there are two competing schools of thought: the "exemplarist" school (Brands' term) which holds that what America chiefly owes the world is the benign example of a well-functioning democracy, and the "vindicationist" school which argues that force must sometimes supplement a good example. In this book, H.W. Brands traces the (...) evolution of these two schools as they emerged in the thinking and writing of the most important public thinkers of the past two centuries. (shrink)

Descartes, René, 1596-1650; Modern philosophy.

Little attention has been given in medical ethics literature to issues relating to the truthfulness of patients. Beginning with an actual medical case, this paper first explores truth-telling by doctors and patients as related to two prominent models of the physician-patient relationship. Utilizing this discussion and the literature on the truthfulness and accuracy of the information patients convey to doctors, these models are then critically assessed. It is argued that the patient agency (patient autonomy or contractual) model is inherently and (...) seriously flawed in numerous circumstances, even those involving informed and competent adult patients. (shrink)